The causative factors of nasal polyps should drive their management. Unfortunately, most cases have unclear etiology. Oral corticosteroids are the most effective medical treatment for most nasal polyps. These nonspecific anti-inflammatory agents rapidly improve symptoms and substantially reduce the size of inflammatory polyps. Patients who respond to oral corticosteroids may be safely retreated three to four times a year if surgery is not an option. Corticosteroids have also proven to be effective when administered intramuscularly or injected into the polyps.
Macrolide antibiotics play a possible role in the management of nasal polyposis, as do topical diuretic therapy and intranasal lysine acetylsalicylate. Intranasal steroid sprays may effectively slow the growth of small nasal polyps but are less effective in treating large nasal polyps. The US Food and Drug Administration has approved dupilumab to treat adults with inadequately controlled, severe chronic rhinosinusitis with nasal polyps.
Learn more about the treatment of nasal polyps.
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Cite this: Arlen D. Meyers. Fast Five Quiz: Sinus Conditions - Medscape - Oct 24, 2022.