TP53 mutation is a well-established prognostic biomarker associated with poor prognosis and an inferior response to standard front-line therapies. In addition, risk stratification models have been established, including Ki67 index, age, lactate dehydrogenase levels, performance status, and white blood cell count.
Further, blastoid morphology as well as time to progression after front-line therapy indicate aggressive disease.
Learn more about MCL.
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Cite this: Ann S. LaCasce. Fast Five Quiz: Non-Hodgkin's Lymphoma: Mantle Cell Lymphoma Practice Essentials - Medscape - May 22, 2023.
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