Upon physical examination, generalized lymphadenopathy is present in 75% of patients. Many patients present with splenomegaly, which may be massive. However, only 20% have poor performance status at presentation. GI tract involvement is common and occurs in 26% of patients.
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Cite this: Ann S. LaCasce. Fast Five Quiz: Signs and Symptoms of Mantle Cell Lymphoma - Medscape - Feb 07, 2023.