Fast Five Quiz: Multiple Sclerosis Diagnosis and Workup

Christopher Luzzio, MD


November 22, 2022

Multiple sclerosis (MS) is an autoimmune chronic inflammatory disease encompassing inflammatory demyelination with axonal transection. According to the Multiple Sclerosis International Federation, as of 2020, there were 2.8 million people living with MS worldwide. Further, approximately 1 million people in the United States are living with MS. In most cases, MS presents during young adulthood; within 20-25 years, significant physical disability ensues in > 30% of cases. MS attacks or exacerbations are characterized by symptoms that reflect central nervous system (CNS) involvement (eg, paresthesias, optic neuritis, and trigeminal neuralgia). The presence of symptomatic episodes separated in time and space, that is, occurring months or years apart and affecting different anatomic locations, is a diagnostic requirement.

An early diagnosis to enable early treatment initiation is crucial to slow disease progression and minimize disability associated with the disease.

How familiar are you with the diagnosis and workup of MS? Test your knowledge with this quick quiz.


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.