According to the 2021 STI treatment guidelines from the CDC, high single-dose therapy is appropriate for a number of STIs. Azithromycin offers the convenience of a high single-dose therapy; however, more than half of patients who receive it experience diarrhea. Other common adverse effects that more than 10% of patients experience include nausea, abdominal pain, and loose stools.
Less common adverse effects include:
Elevated alanine transaminase, aspartate transaminase, and creatinine
Elevated lactate dehydrogenase and bilirubin
Decreased platelet count
Elevated serum alkaline phosphatase
Learn more about azithromycin.
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Cite this: Mary L. Windle. Rapid Rx Quiz: Sexually Transmitted Infection Drug Treatments - Medscape - Nov 18, 2022.