Fast Five Quiz: Schizophrenia Practice Essentials

Steve Soreff, MD


November 22, 2022

Extrapyramidal symptoms, including akathisia, dystonia, muscle stiffness, parkinsonism, and tardive dyskinesia, are among the most common and troubling adverse effects of thioridazine, occurring in as many as 60% of patients. Other adverse effects include:

  • Agitation

  • Anorexia

  • Anticholinergic effects

  • Anxiety

  • Blood dyscrasia

  • Cerebral edema

  • Constipation

  • Depression

  • Diarrhea

  • Dizziness

  • Dyspepsia

  • ECG changes

  • Ejaculatory disorder

  • Erectile dysfunction

  • Euphoria

  • Galactorrhea

  • Headache

  • Ileus

  • Insomnia

  • Oligomenorrhea/amenorrhea

  • Orthostatic hypotension

  • Photosensitivity

  • Poikilothermia

  • Pruritis

  • Restlessness

  • Sedation

  • Tachycardia

  • Weakness

  • Weight gain

  • Lens opacities (prolonged use)

  • Neuroleptic malignant syndrome (infrequent but serious)

  • Cholestatic jaundice (rare)

  • Seizure (rare)

  • Priapism (rare)

Learn more about thioridazine.

This Fast Five Quiz was excerpted and adapted from the Medscape articles Schizophrenia, Childhood-Onset Schizophrenia, and Thioridazine.

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