Approximately 5%-10% of breast cancers are diagnosed in patients carrying germline pathogenic variants in highly penetrant hereditary breast cancer genes, with BRCA1/2 being the most common. BRCA-associated breast cancers tend to present at younger ages than sporadic cancers and are associated with a higher risk for synchronous or metachronous contralateral breast and ovarian cancer. Genetic testing can inform both locoregional and systemic treatment.
How much do you know about BRCA-mutated metastatic breast cancer (MBC)? Test yourself with this quick quiz.
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Cite this: Stefania Morganti. Fast Five Quiz: BRCA-Associated Metastatic Breast Cancer - Medscape - Apr 19, 2023.