Fast Five Quiz: Chronic Kidney Disease Signs and Symptoms

Patrick Rossignol, MD


February 03, 2023

According to Arora and colleagues, individuals who are inadequately dialyzed experience the following manifestations of uremia:

  • Pericarditis: Can be complicated by cardiac tamponade, possibly resulting in death if unrecognized

  • Encephalopathy: Can progress to coma and death

  • Peripheral neuropathy, usually asymptomatic

  • Restless leg syndrome

  • Gastrointestinal symptoms: Anorexia, nausea, vomiting, and diarrhea

  • Skin manifestations, such as dry skin, pruritus, and ecchymosis

  • Fatigue, increased somnolence, and failure to thrive

  • Malnutrition

  • Erectile dysfunction, decreased libido, and amenorrhea

  • Platelet dysfunction with tendency to bleed

Learn more about the signs and symptoms of CKD and ESRD.

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