Fast Five Quiz: Guillain-Barré Syndrome Practice Essentials

Helmi L. Lutsep, MD


December 06, 2022

Mean time to clinical function nadir is 12 days, with 98% of patients reaching it within 4 weeks. Patients with GBS typically present 2-4 weeks after a relatively benign respiratory or gastrointestinal illness, with complaints of proximal muscle weakness of the lower extremities and finger dysesthesias. Weakness may progress to involve the truncal muscles, arms, and eventually the cranial nerves and muscles of respiration; it is atypical for GBS to begin in the head and face.

As many as two thirds of patients with GBS report an antecedent illness or event 1-3 weeks prior to the onset of weakness.

Learn more about the clinical presentation of GBS.


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