Fast Five Quiz: Pharyngitis (Sore Throat)

Richard H. Sinert, DO


December 14, 2022

In terms of the clinical presentation of pharyngitis, although tender anterior cervical nodes are consistent with streptococcal infection, generalized adenopathy is consistent with infectious mononucleosis or the acute lymphoglandular syndrome of HIV infection. Hepatosplenomegaly and scleral icterus also may be seen with infectious mononucleosis, and tonsillopharyngeal/palatal petechiae are seen in infectious mononucleosis and GAS infections.

Murmurs should be documented in an acute episode of pharyngitis to monitor for potential rheumatic fever. Oropharyngeal vesicular lesions and concomitant vesicles on the hands and feet are seen in coxsackievirus infection (also called hand-foot-and-mouth disease). Pharyngitis with lower respiratory tract infections is common with M pneumoniae infection, particularly when a persistent nonproductive cough is present.

Learn more about Epstein-Barr virus infectious mononucleosis.


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