Narcolepsy is a rare, chronic central nervous system (CNS) hypersomnia. Pharmacologic treatment for narcolepsy is centered on symptomatic treatment of excessive daytime sleepiness (EDS) and cataplexy with CNS stimulants and CNS depressants; stimulants improve wakefulness, and antidepressants reduce the frequency of cataplectic episodes. The objective of most symptomatic treatment strategies should be to improve the sleep-awake cycle, with a special focus on daytime functioning. Of note, guidelines from the American Academy of Sleep Medicine are designed in support of individual mediations rather than entire medication classes.
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Cite this: Heidi Moawad. Fast Five Quiz: Treatment of Narcolepsy - Medscape - Feb 06, 2023.
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