Analyzing a subset of participants in the PESA study who were middle-aged and apparently healthy, Raposeiras-Roubin and colleagues examined the association between serum triglycerides and atherosclerosis. They found that significantly higher prevalence of noncoronary atherosclerosis in individuals with serum triglycerides was ≥ 3.88 mmol/L. This association was found in individuals with high LDL-C and in those with normal LDL-C. In addition, serum triglycerides were associated with general arterial inflammation and with inflamed atherosclerotic plaques.
Current European guidelines recommend the initiation of statins for serum triglycerides > 5.17 mmol/L for patients at high CVD risk.
Learn more about the presentation of hypertriglyceridemia.
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Cite this: Romesh Khardori. Fast Five Quiz: Triglycerides as an Independent Cardiovascular Disease Risk Factor - Medscape - Mar 10, 2023.