Fast Five Quiz: Triglycerides as an Independent Cardiovascular Disease Risk Factor

Romesh Khardori, MD, PhD


March 10, 2023

In the general population, individuals with nonfasting triglyceride level of 6.6 mmol/L have increased risk for myocardial infarction, ischemic heart disease, ischemic stroke, and all-cause mortality compared with individuals with a level of 0.8 mmol/L.

The REDUCE-IT study identified a lower risk for ischemic events among the patients with high fasting triglyceride levels who were treated with a statin and received icosapent ethyl than those who received placebo.

Triglyceride-rich lipoproteins and their remnants have been shown to be independently associated with increased lipid-related risk for CVD.

A recent study by Nordestgaard and colleagues revealed that high levels of triglyceride molecules in LDL-C are robustly linked to increased risk for atherosclerotic CVD.

Learn more about hypertriglyceridemia.

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