Fast Five Quiz: Herpes Zoster Prevention in Adults Who Are Immunocompromised

Heidi Moawad, MD


May 04, 2023

Patients who are immunocompromised are at risk for HZ recurrence, as well as atypical and/or more severe disease. Other factors that influence HZ recurrence are older age and zoster-related pain > 30 days. The recurrence rate has been calculated at 12 cases per 1000 person years.

Special clinical presentations of HZ, including disseminated HZ, central nervous system HZ, and HZ opthalmicus, are more common among patients who are immunocompromised than those who are immunocompetent. Hematologic and solid cancers are associated with an increase in the risk for HZ, as is chemotherapy.

Learn more about special risks for HZ in immunocompromised populations.


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