Rapid Rx Quiz: Dangerous Drug Combinations

Mary L. Windle, PharmD


March 13, 2023

Cabotegravir/rilpivirine is a long-acting injectable for HIV infection, used in patients who have attained viral suppression on another antiretroviral regimen. Drugs that induce cytochrome CYP3A enzymes significantly decrease plasma concentrations of cabotegravir and/or rilpivirine, which may cause a dangerous loss of virologic response. These drugs include rifampin, dexamethasone, and oxcarbazepine.

Learn more about cabotegravir/rilpivirine.

This Rapid Review Quiz was excerpted and adapted from the Medscape articles: Warfarin, Atorvastatin, Real-World Data Suggest Coprescribing PDE5 Inhibitors and Nitrates May Be Safe, Nitroglycerin PO, Spironolactone, Hyperkalemia, Ciprofloxacin, and Theophylline Toxicity.

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