The most predictive factors for the risk for severe illness with SARS-CoV-2 reinfection are age and the disease severity at the first episode. Although cases of COVID caused by reinfection appear to have a milder disease course, age may increase the risk for death in all cases, with adults aged > 50 years having 57 times the odds of dying compared with younger adults and children in the 28 days after testing positive.
The Omicron variant appears to be associated with less severe clinical outcomes.
Learn more about COVID-19 risk factors.
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Cite this: Enrico Brunetti. Fast Five Quiz: Risk Factors for SARS-CoV-2 Reinfection - Medscape - Apr 14, 2023.