According the KDIGO guidelines, patients with IgA nephropathy who are at high risk for rapid disease progression despite maximal supportive care for at least 3 months should receive a 6-month course of immunosuppression with glucocorticoid therapy.
Mycophenolate mofetil can be used as a potential glucocorticoid-sparing treatment agent for patients that remain steroid dependent or steroid resistant.
Editor's Note: Skill Checkups are wholly fictional or fictionalized clinical scenarios intended to provide evidence-based educational takeaways.
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Cite this: A. Brent Alper. Skill Checkup: A 56-Year-Old Man With Primary IgA Nephropathy and Fatigue, Abdominal Pain, and Frothy Urine - Medscape - May 01, 2023.