The first step in the workup of IgA nephropathy is a thorough urinalysis of a first-void urine sample. Examination of the urine sediment is necessary to identify any trace of hematuria. Once a thorough urinalysis is performed, diagnosis should be confirmed via renal biopsy.
After urinalysis (or simultaneously, depending upon presenting symptoms), basic biochemistry (blood work) can be performed to rule out any other causes of hematuria as well as to measure protein and cholesterol levels.
Imaging (eg, cystoscopy) can be considered later on in the diagnostic process to pinpoint the source of the hematuria and also to rule out kidney stones and bladder cancer.
Learn more about the workup of IgA nephropathy.
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Cite this: A. Brent Alper. Fast Five Quiz: IgA Nephropathy Presentation and Diagnosis - Medscape - Sep 18, 2023.